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Apoptosis is a type of programmed cell death that occurs normally throughout the lifespan and can also occur in response to harmful stimuli. Apoptotic cells are identified by their altered morphology, caspase activation, and the presence of damaged DNA.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Products and Related Resources for Cell Death and Viability SARS-CoV-2 Research
Regulation of cell death due to viral infection is important for host survival. In this series, we look at pathways regulated through cellular responses to viruses.
These markers can be used to study necroptosis and pyroptosis, forms of regulated necrotic cell death that share morphological features with necrosis.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Pyroptosis is a type of programmed necrotic cell death activated by infections from bacteria, viruses, fungi or protozoa in the presence of PAMPs or DAMPs
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Cell viability is a measure of the proportion of live, healthy cells within a population. Assays to assess cell viability measure metabolic activity, ATP content, cell proliferation, or membrane integrity.
细胞焦亡与其他多种细胞程序性死亡形式之间存在相互联系和转化，共同构成细胞程序性死亡的复杂体系，维持细胞和机体的内稳态。
Caspase Cleavage Substrate Proteomics
A scientific resource for the CSD protein domain containing information on structure, function, and domain binding during chromatin remodeling.
Overview of GPCR, Calcium, cAMP Signaling Resources, interactive pathway diagrams, and other technical resources.
Immunohistochemistry Protocol - Frozen for Boost Detection Reagent: easy to follow directions describing the step by step experimental procedure.
A scientific resource for the death protein domain containing information on structure, function, and domain binding during apoptosis.
A scientific resource for the DED protein domain containing information on structure, function, and domain binding during apoptosis.
An orthogonal strategy for antibody validation involves cross-referencing antibody-based results with data obtained using non-antibody-based methods.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
Validation for flow cytometry antibodies from CST Cell Signaling Technology
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Our summary of recent findings published in Nature, which indicate that non-performing antibodies were used in many recent macular degeneration studies.
KinomeView® Profiling Kit and Services
A scientific resource for the TPR protein domain containing information on structure, function, and domain binding in cell cycle-associated proteins.
Immunoprecipitation Protocol (For Native Protein): easy to follow directions describing the step by step experimental procedure.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
A scientific resource for the FF protein domain containing information on structure, function, and binding to phospho-serine motifs.
Scientific posters presented by CST scientists at various conferences and trade shows through the years.
