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ANT2/SLC25A5 Antibody #12546
This product is discontinued
Gallery: ANT2/SLC25A5 Antibody #12546
ANT2/SLC25A5 Antibody recognizes endogenous levels of total ANT2/SLC25A5 protein.
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly158 of human ANT2/SLC25A5 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Adenine nucleotide translocase 2 (ANT2/SLC25A5) is a member of the adenine nucleotide translocase family of mitochondrial inner membrane proteins that function differently in metabolic and apoptotic pathways (1). Research studies indicate that ANT2 expression in undifferentiated, proliferating cells correlates with the rate of glycolytic metabolism and may be an indicator of carcinogenesis (2). Suppression of ANT2/SLC25A5 expression by specific RNA interference in human breast cancer cells promotes apoptosis and inhibits tumor cell growth (2), which suggests a cytoprotective role of ANT2/SLC25A5 (1,3).
For Research Use Only. Not For Use In Diagnostic Procedures. Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.