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NCBP1/CBP80 Antibody #9983
This product is discontinued
Gallery: NCBP1/CBP80 Antibody #9983
NCBP1/CBP80 recognizes endogenous levels of total NCBP1/CBP80 protein.
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val452 of human NCBP1/CBP80 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Nuclear cap-binding protein subunit 1 (NCBP1), also known as cap-binding protein 80 (CBP80), plays a role in nuclear pre-mRNA splicing (1,2). It has also been shown to function in the nonsense-mediated decay (NMD) of mRNAs where translation is prematurely terminated (3). NCBP1/CBP80 increases the efficiency of NMD by promoting the interaction of two active NMD components Upf1 and Upf2 (4).
For Research Use Only. Not For Use In Diagnostic Procedures. Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.