Product Pathways - Neuroscience
RAIG1 (D4S7D) XP® Rabbit mAb #12968
|12968S||100 µl (10 western blots)||---||In Stock||---|
|12968P||40 µl (4 western blots)||---||In Stock||---|
|12968||carrier free and custom formulation / quantity||email request|
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Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting, IP=Immunoprecipitation, IHC-P=Immunohistochemistry (Paraffin), IF-IC=Immunofluorescence (Immunocytochemistry)
Specificity / Sensitivity
RAIG1 (D4S7D) XP® Rabbit mAb recognizes endogenous levels of total RAIG1 protein.
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val295 of human RAIG1 protein.
Western blot analysis of extracts from various cell lines using RAIG1 (D4S7D) XP® Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8547 (lower)
Immunohistochemical analysis of paraffin-embedded breast carcinoma using RAIG1 (D4S7D) XP® Rabbit mAb.
Immunohistochemical analysis of paraffin-embedded human normal lung using RAIG1 (D4S7D) XP® Rabbit mAb.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using RAIG1 (D4S7D) XP®Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).
Retinoic Acid-Induced Gene 1 (RAIG1), also called RAI3 and GPRC5A, belongs to the family of G protein-coupled receptors (GPCRs). GPCRs are the largest and most abundant receptor family in mammals, composed of more than one thousand members (1). Retinoic acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. It is thought that RAIG1 may be a downstream target of RA signaling (2). RAIG1 is expressed in lung tissue and in several lung cancer cell lines, and encodes a seven-transmembrane glycoprotein presumed to be a lung tumor suppressor gene (3,4).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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