Ibrutinib is supplied as a lyophilized powder. For a 10mM stock, reconstitute the 5 mg of powder in 1.14 ml DMSO. Working concentrations and length of treatment can vary depending on the desired effect, but it is typically used as a pretreatment at 1-10 μM for 1 hour prior to treating with a stimulator.
Store lyophilized or in solution at -20C, dessicated. Protect from light. In lyophilized form, the chemical is stable for 24 months. Once in solution, use within 3 months to prevent loss of potency. Aliquot to avoid mulitple freeze/thaw cycles.
|Molecular Weight||440.5 g/mol|
|Solubility||Soluble in DMSO at 200mg/ml and EtOH at 25mg/ml.|
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