| Product Includes | Product # | Quantity | Mol. Wt | Isotype/Source |
|---|---|---|---|---|
| Cleaved Caspase-3 (Asp175) (D3E9) Rabbit mAb (Alexa Fluor® 488 Conjugate) | 9603 | 40 µl | Rabbit IgG | |
| Cleaved PARP (Asp214) (D64E10) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) | 9148 | 40 µl | 89 kDa | Rabbit IgG |
| Ki-67 (D3B5) Rabbit mAb (Alexa Fluor® 488 Conjugate) | 11882 | 40 µl | Rabbit IgG | |
| Rabbit (DA1E) mAb IgG XP® Isotype Control (Alexa Fluor® 488 Conjugate) | 2975 | 40 µl | Rabbit IgG |
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Description
The Apoptosis and Proliferation Alexa Fluor® 488 Conjugated Antibody Sampler Kit provides an economical means to study apoptosis and proliferation status using known markers without the need for a fluorescent secondary antibody.
Storage
Background
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). PARP is involved in DNA repair in response to environmental stress (2). Ki-67 is a nuclear nonhistone protein that is universally expressed among proliferating cells and absent in quiescent cells (3,4). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase.
Background References
Trademarks and Patents
Limited Uses
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