Revision 1
#9955
Store at -20C
4E-BP Antibody Sampler Kit
1 Kit
(6 x 20 microliters)
877-616-CELL (2355)
877-678-TECH (8324)
3 Trask Lane | Danvers | Massachusetts | 01923 | USA
For Research Use Only. Not for Use in Diagnostic Procedures.
| Product Includes | Product # | Quantity | Mol. Wt | Isotype/Source |
|---|---|---|---|---|
| Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb | 2855 | 20 µl | 15 to 20 kDa | Rabbit IgG |
| Non-phospho-4E-BP1 (Thr46) (87D12) Rabbit mAb | 4923 | 20 µl | 15-20 kDa | Rabbit IgG |
| Phospho-4E-BP1 (Ser65) Antibody | 9451 | 20 µl | 15 to 20 kDa | Rabbit |
| 4E-BP1 (53H11) Rabbit mAb | 9644 | 20 µl | 15-20 kDa | Rabbit IgG |
| 4E-BP2 Antibody | 2845 | 20 µl | 15 to 20 kDa | Rabbit |
| Phospho-4E-BP1 (Thr70) Antibody | 9455 | 20 µl | 15 to 20 kDa | Rabbit |
| Anti-rabbit IgG, HRP-linked Antibody | 7074 | 100 µl | Goat |
Please visit cellsignal.com for individual component applications, species cross-reactivity, dilutions, protocols, and additional product information.
Description
Storage
Background
4E-BP2 and 4E-BP3 share high sequence homology with 4E-BP1, including conservation of the major FRAP/mTOR-dependent phosphorylation sites. Preliminary data suggests that phosphorylation of 4E-BP2 is regulated in a similar manner to that of 4E-BP1, although phosphorylation of this protein has not been as extensively studied (6).
Background References
- Pause, A. et al. (1994) Nature 371, 762-7.
- Brunn, G.J. et al. (1997) Science 277, 99-101.
- Gingras, A.C. et al. (1998) Genes Dev 12, 502-13.
- Fadden, P. et al. (1997) J Biol Chem 272, 10240-7.
- Gingras, A.C. et al. (1999) Genes Dev 13, 1422-37.
- Lin, T.A. and Lawrence, J.C. (1996) J. Biol. Chem. 271, 30199-30204.
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Limited Uses
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