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877-616-CELL (2355)

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Support:

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For Research Use Only. Not for Use in Diagnostic Procedures.

Product Includes Product # Quantity Mol. Wt Isotype/Source
Myelin Basic Protein (E9P7U) Mouse Monoclonal Antibody8368320 µl12-18 kDaMouse IgG2b kappa
PLP1 (E9V1N) Rabbit Monoclonal Antibody2870220 µl20-30 kDaRabbit IgG
MOG (E5K6T) Rabbit Monoclonal Antibody9645720 µl46, 35, 28, 23 kDaRabbit IgG
MAG (D4G3) Rabbit Monoclonal Antibody904320 µl100 kDaRabbit IgG
Caspr (D8I3V) Rabbit Monoclonal Antibody9773620 µl190 kDaRabbit IgG
Caspr2 (D6S1O) Rabbit Monoclonal Antibody6196220 µl150 kDaRabbit IgG
Neurofascin 155 (D7B6O) Rabbit Monoclonal Antibody1503520 µl140-155 kDaRabbit IgG
Neurofascin 186 (D6G6O) Rabbit Monoclonal Antibody1503420 µl200 kDaRabbit IgG
beta3-Tubulin (D71G9) Rabbit Monoclonal Antibody556820 µl55 kDaRabbit IgG
Anti-rabbit IgG, HRP-linked Antibody7074100 µlGoat

Please visit cellsignal.com for individual component applications, species cross-reactivity, dilutions, protocols, and additional product information.

Description

The Demyelinating Disease Targets Antibody Sampler Kit provides an economical means of detecting the protein components of myelin sheath. The kit includes enough antibodies to perform two western blot experiments with each primary antibody.

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibodies.

Background

Myelin is the insulating material surrounding neuronal axons. The function of myelin is to promote action potential propagation down the axon to the axon terminal. Myelin is formed in the central nervous system (CNS) by specialized glial cells called oligodendrocytes and by Schwann cells in the peripheral nervous system (PNS). Oligodendrocytes and Schwann cells make concentric rings, called the myelin sheath, around the axon at regular intervals. These intervals, called nodes of ranvier, are enriched in structural proteins and ion channels, which help promote action potential propagation. Several proteins are enriched in the myelin sheath and likely help mediate the tight multi-layered membranes that make up the sheath. These proteins include myelin basic protein (MBP, [1]), myelin-associated glycoprotein (MAG, [2]), myelin proteolipid protein (PLP1, [3]) and  myelin-oligodendrocyte glycoprotein (MOG, [4]). Contactin-associated protein (Caspr) 1 & 2 (5,6) and neurofascin 155 & 186 (7,8) are nodes of ranvier-associated proteins that may play roles in generating the regular intervals of myelin along the axon. Expression of several of these proteins are altered in demyelinating diseases such as multiple sclerosis (MS). Additionally, mislocalization and/or altered expression of these proteins, compared to the axonal protein β3-tubulin, may represent altered myelin function. 

Trademarks and Patents

Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.

All other trademarks are the property of their respective owners. Visit cellsignal.com/trademarks for more information.

Limited Uses

Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect.

Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.

Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Western blot analysis of extracts from mouse brain, mouse lung, and rat brain using Neurofascin 186 (D6G6O) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).
undefined Image 1: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from mouse brain, mouse lung, and rat brain using Neurofascin 155 (D7B6O) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).
undefined Image 2: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from various tissues using PLP1 (E9V1N) Rabbit mAb (upper) and α-Actinin (D6F6) XP® Rabbit mAb #6487 (lower). The upper band corresponds to the full-length PLP1 while the lower band is an alternative splice from PLP1 known as DM20.
undefined Image 3: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Immunohistochemical analysis of paraffin-embedded human Alzheimer's brain using PLP1 (E9V1N) Rabbit mAb.
undefined Image 4: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of HeLa and human cerebellum using β3-Tubulin (D71G9) XP® Rabbit mAb.
undefined Image 5: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from mouse and rat brain using Caspr2 (D6S1O) Rabbit mAb.
undefined Image 6: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
After the primary antibody is bound to the target protein, a complex with HRP-linked secondary antibody is formed. The LumiGLO® is added and emits light during enzyme catalyzed decomposition.
undefined Image 7: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from various tissues and cell lines using Myelin Basic Protein (E9P7U) Mouse mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).
undefined Image 8: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from mouse brain, rat brain, and human cerebellum using MAG (D4G3) XP® Rabbit mAb.
undefined Image 9: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Western blot analysis of extracts from various tissues using MOG (E5K6T) XP® Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).
undefined Image 10: Demyelinating Disease Targets Antibody Sampler Kit
Western blot analysis of extracts from mouse brain, mouse pancreas, human cerebellum, and human pancreas using Caspr (D8I3V) Rabbit mAb (Upper) and α-Actinin (D6F6) XP® Rabbit mAb (HRP Conjugate) #12413 (Lower).
undefined Image 11: Demyelinating Disease Targets Antibody Sampler Kit
Immunoprecipitation of Neurofascin 186 from mouse brain extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or Neurofascin 186 (D6G6O) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using Neurofascin 186 (D6G6O) Rabbit mAb.
undefined Image 12: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Confocal immunofluorescent analysis of mouse sciatic nerve using Neurofascin 186 (D6G6O) Rabbit mAb (left, green) or Neurofascin 155 (D7B6O) Rabbit mAb # 15035 (right, green). Neurofilament-L protein was labeled with Neurofilament-L (DA2) Mouse mAb #2835 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 13: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of mouse cerebellum (left) and striatum (right) using PLP1 (E9V1N) Rabbit mAb (green) and GFAP (GA5) Mouse mAb #3670 (red). Samples were mounted in ProLong® Gold Antifade Reagent with DAPI #8961 (blue).
undefined Image 14: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded human glioma using PLP1 (E9V1N) Rabbit mAb.
undefined Image 15: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Confocal immunofluorescent analysis of mouse cerebellum using β3-Tubulin (D71G9) XP® Rabbit mAb (green) and Tau (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 16: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of mouse brain using Myelin Basic Protein (E9P7U) Mouse mAb (green) and PDGF Receptor α (D1E1E) XP® Rabbit mAb #3174 (red). Samples were mounted in Prolong® Gold Antifade Reagent with DAPI #8961 (blue).
undefined Image 17: Demyelinating Disease Targets Antibody Sampler Kit
Simple Western™ analysis of lysates (0.1 mg/mL) from Mouse Brain tissue using MAG (D4G3) XP® Rabbit mAb #9043. The virtual lane view (left) shows the target band (as indicated) at 1:10 and 1:50 dilutions of primary antibody. The corresponding electropherogram view (right) plots chemiluminescence by molecular weight along the capillary at 1:10 (blue line) and 1:50 (green line) dilutions of primary antibody. This experiment was performed under reducing conditions on the Jess™ Simple Western instrument from ProteinSimple, a BioTechne brand, using the 66-440 kDa separation module.
undefined Image 18: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Immunohistochemical analysis of paraffin-embedded human cerebellum using MOG (E5K6T) XP® Rabbit mAb.
undefined Image 19: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of mouse sciatic nerve using Caspr (D8I3V) Rabbit mAb (green). Actin filaments were labeled with DyLight™ 554 Phalloidin #13054 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 20: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of mouse sciatic nerve using Neurofascin 186 (D6G6O) Rabbit mAb (left, green) or Neurofascin 155 (D7B6O) Rabbit mAb # 15035 (right, green). Neurofilament-L protein was labeled with Neurofilament-L (DA2) Mouse mAb #2835 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 21: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Confocal immunofluorescent analysis of rat spinal cord using Neurofascin 186 (D6G6O) Rabbit mAb (left, green) or Neurofascin 155 (D7B6O) Rabbit mAb # 15035 (right, green). β3-Tubulin protein was labeled with β3-Tubulin (TU-20) Mouse mAb #4466 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 22: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded human glioblastoma using PLP1 (E9V1N) Rabbit mAb.
undefined Image 23: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of P19 cells that were differentiated with retinoic acid, using β3-Tubulin (D71G9) XP® Rabbit mAb (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5 #4084® (fluorescent DNA dye).
undefined Image 24: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Confocal immunofluorescent analysis of mouse hippocampus (left, zoomed out) or (right, zoomed in) using Myelin Basic Protein (E9P7U) Mouse mAb (green, mouse IgG2b) and Synaptophysin (7H12) Mouse mAb (IF Formulated) #9020 (red, mouse IgG1). Samples were mounted in ProLong® Gold Antifade Reagent with DAPI #8961 (blue).
undefined Image 25: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of rat cerebellum using MAG (D4G3) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 26: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded mouse brain using MOG (E5K6T) XP® Rabbit mAb.
undefined Image 27: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Confocal immunofluorescent analysis of rat spinal cord using Neurofascin 186 (D6G6O) Rabbit mAb (left, green) or Neurofascin 155 (D7B6O) Rabbit mAb # 15035 (right, green). β3-Tubulin protein was labeled with β3-Tubulin (TU-20) Mouse mAb #4466 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
undefined Image 28: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded normal human brain using PLP1 (E9V1N) Rabbit mAb.
undefined Image 29: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded mouse cerebellum (left, positive) or colon (right, negative) using MOG (E5K6T) XP® Rabbit mAb. Note the lack of staining of the myenteric plexus ganglion cells in the mouse colon.
undefined Image 30: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Immunohistochemical analysis of paraffin-embedded mouse cerebellum (left, positive), small intestine (middle, negative), or LL/2 syngeneic tumor (right, negative) using PLP1 (E9V1N) Rabbit mAb.
undefined Image 31: Demyelinating Disease Targets Antibody Sampler Kit
Immunoprecipitation of β3-Tubulin from mouse brain tissue extracts. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, and lane 3 is β3-Tubulin (D71G9) XP® Rabbit mAb. Western blot analysis was performed using β3-Tubulin (D71G9) XP® Rabbit mAb. Mouse Anti-rabbit IgG (Conformation Specific) (L27A9) mAb #3678 was used as the secondary antibody.
undefined Image 32: Demyelinating Disease Targets Antibody Sampler Kit
Immunohistochemical analysis of paraffin-embedded rat brain using MOG (E5K6T) XP® Rabbit mAb.
undefined Image 33: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Immunohistochemical analysis of paraffin-embedded normal human brain using PLP1 (E9V1N) Rabbit mAb (left) compared to concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (right).
undefined Image 34: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of fixed frozen mouse subiculum from wild-type (left) or an amyloid mouse model of Alzheimer's disease (right) using PLP1 (E9V1N) Rabbit mAb (green). After blocking free secondary antibody binding sites with Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, the tissue was then labeled using β-Amyloid (D54D2) XP® Rabbit mAb (Alexa Fluor® 594 Conjugate) #35363 (red) and ProLong® Gold Antifade Reagent with DAPI #8961 (blue).
undefined Image 35: Demyelinating Disease Targets Antibody Sampler Kit
Confocal immunofluorescent analysis of fixed frozen mouse hippocampus from wild-type (left) or an amyloid mouse model of Alzheimer's disease (right) using PLP1 (E9V1N) Rabbit mAb (green). After blocking free secondary antibody binding sites with Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, the tissue was then labeled using Iba1/AIF-1 (E4O4W) XP® Rabbit mAb (Alexa Fluor® 555 Conjugate) (red) and ProLong® Gold Antifade Reagent with DAPI #8961 (blue).
undefined Image 36: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Simple Western™ analysis of lysates (0.05 mg/mL) from mouse brain tissue using PLP1 (E9V1N) Rabbit mAb #28702. The virtual lane view (left) shows the target band (as indicated) at 1:10 and 1:50 dilutions of primary antibody. The corresponding electropherogram view (right) plots chemiluminescence by molecular weight along the capillary at 1:10 (blue line) and 1:50 (green line) dilutions of primary antibody. This experiment was performed under reducing conditions on the Jess™ Simple Western instrument from ProteinSimple, a BioTechne brand, using the 12-230 kDa separation module.
undefined Image 37: Demyelinating Disease Targets Antibody Sampler Kit
Cyclic multiplex immunofluorescent analysis of fixed frozen hippocampus in a normal mouse (left) or an amyloid mouse model of Alzheimer's Disease (right) using PLP1 (E9V1N) Rabbit mAb (red). After blocking free secondary antibody binding sites with Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, the tissues were then labeled using Myelin Basic Protein (D8X4Q) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) #30103 (green) and β-Amyloid (D54D2) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) #51374 (cyan). Sections were mounted in ProLong Gold Antifade Reagent with DAPI #8961 (blue) and then imaged. After imaging, sections were processed in Western Blot Stripping Buffer (5X) #91925 to remove bound primary and secondary antibody. Then sections were labeled with GFAP (E4L7M) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) #94242 (gray) and Iba1/AIF-1 (E4O4W) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) #78060 (magenta). Sections were mounted in ProLong Gold Antifade Reagent with DAPI #8961 (blue) and then imaged a second time.
undefined Image 38: Demyelinating Disease Targets Antibody Sampler Kit
Cyclic multiplex immunofluorescent analysis of fixed frozen cortex in a normal mouse (left) or an amyloid mouse model of Alzheimer's Disease (right) using PLP1 (E9V1N) Rabbit mAb #28702 (red). After blocking free secondary antibody binding sites with Rabbit (DA1E) mAb IgG XP® Isotype Control #3900, the tissues were then labeled using Myelin Basic Protein (D8X4Q) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) #30103 (green) and β-Amyloid (D54D2) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) #51374 (cyan). Sections were mounted in ProLong Gold Antifade Reagent with DAPI #8961 (blue) and then imaged. After imaging, sections were processed in Western Blot Stripping Buffer (5X) #91925 to remove bound primary and secondary antibody. Then sections were labeled with GFAP (E4L7M) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate) #94242 (gray) and Iba1/AIF-1 (E4O4W) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) #78060 (magenta). Sections were mounted in ProLong Gold Antifade Reagent with DAPI #8961 (blue) and then imaged a second time.
undefined Image 39: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.

Revision 1

Cell Signaling Technology Logo
Simple WesternTM analysis of lysates (0.05 mg/ml) from rat brain using Myelin Basic Protein (E9P7U) Mouse mAb #83683. The virtual lane view (left) shows the target band (as indicated) at 1:50 and 1:250 dilutions of primary antibody. The corresponding electropherogram view (right) plots chemiluminescence by molecular weight along the capillary at 1:50 (blue line) and 1:250 (green line) dilutions of primary antibody. This experiment was performed under reducing conditions on the JessTM Simple Western instrument from ProteinSimple, a BioTechne brand, using the 66-440kDa.
undefined Image 40: Demyelinating Disease Targets Antibody Sampler Kit
Simple Western™ analysis of lysates (0.1 mg/mL) from Mouse Brain tissue using MOG (E5K6T) XP® Rabbit mAb #96457. The virtual lane view (left) shows the target band (as indicated) at 1:50 and 1:250 dilutions of primary antibody. The corresponding electropherogram view (right) plots chemiluminescence by molecular weight along the capillary at 1:50 (blue line) and 1:250 (green line) dilutions of primary antibody. This experiment was performed under reducing conditions on the Jess™ Simple Western instrument from ProteinSimple, a BioTechne brand, using the 12-230 kDa separation module.
undefined Image 41: Demyelinating Disease Targets Antibody Sampler Kit
Orders: 877-616-CELL (2355) [email protected] Support: 877-678-TECH (8324) [email protected] Web: cellsignal.com
For Research Use Only. Not for Use in Diagnostic Procedures.