| # | Product Name | Applications | Reactivity | |
|---|---|---|---|---|
| 4153 | EGR1 (15F7) Rabbit mAb |
|
H M R | |
| 4154 | EGR1 (44D5) Rabbit mAb |
|
H M R |
| REACTIVITY | |
| SENSITIVITY | Endogenous |
| MW (kDa) | 80 |
| SOURCE | Rabbit |
Product Information
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal sequence of human EGR1. Antibodies are purified by protein A and peptide affinity chromatography.
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression (1). The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1,2). Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2,3).
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STRING - Known and Predicted Protein-Protein Interactions.
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