Targeting Cancer Pathways Series

Cell Signaling Technology is proud to partner with the Koch Institute at MIT, Science and Science Signaling to present a series of webinars focused on “Targeting Cancer Pathways.”

We will be updating this page as information becomes available, so check back often.

Targeting Tumor Metabolism

June 11th, 2015

In this webinar we will explore how cancer cells are able to reprogram their metabolic pathways to enable energy production under conditions that are disabling to most normal cells. Of great interest are how tumor-specific metabolic changes promote oncogenic progression and how these changes can be exploited to develop more effective treatment options. During the webinar, the speakers will:

  • Outline the major metabolic changes seen in tumor tissue
  • Explain how specific metabolic pathways can be targeted during therapeutic interventions
  • Introduce the role of autophagy and cell death in tumor survival and progression
  • Answer your questions live during the broadcast!

Featured speakers

Nissim Hay M. Celeste Simon

Nissim Hay, Ph.D
University of Ilinois
Chicago, IL

M. Celeste Simon, Ph.D
University of Pennsylvania
Philadelphia, PA

Upcoming Webinar - August 12, 2015. Targeting Cancer Pathways: The Epigenetic Question

In this webinar the speakers will look at how epigenetic changes to the genome contribute to the progression of cancer.

Ali Shilatifard, Ph.D.
Northwestern University
Chicago, IL

Charles Roberts, M.D., Ph.D.
Dana Farber Cancer Institute
Boston, MA

Stephen B. Baylin, M.D.
Johns Hopkins School of Medicine
Baltimore, MD

On Demand - Targeting Cancer Pathways: Tumor Microenvironment

Here, we will explore how the tumor microenvironment promotes oncogenic progression, while protecting the tumor from therapeutic intervention. By better understanding the tumor microenvironment we can develop strategies and treatment options to neutralize its oncogenic influence and more effectively attack the tumor itself.

Featured speakers

Padmanee Sharma Rakesh Jain

Padmanee Sharma, M.D., Ph.D The University of Texas MD Anderson Cancer Center, Houston, TX.

Rakesh Jain, Ph.D Massachusetts General Hospital, Harvard Medical School, Boston, MA

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On Demand - Targeting Cancer Pathways: Mechanisms of Tumor Resistance

This webinar focuses on how the rewiring of signaling pathways in response to drug treatment contributes to tumor resistance and how this knowledge can be leveraged to develop more effective treatment strategies.

During this webinar, viewers will:

  • Gain an understanding of the specific molecules and pathways that are the targets for rationally designed therapies
  • Learn about efforts to overcome resistance to the first FDA-approved therapy targeting a hyperactive kinase
  • Review mechanisms by which tumor cells resist inhibitors that target cell survival and growth pathways
  • Hear how the rewiring of cell death pathways can sensitize cells to traditional chemotherapy agents

Featured speakers

Yaffe Engelman Deininger
Michael B. Yaffe, M.D., Ph.D. Massachusetts Institute of Technology, Cambridge, MA Jeffrey Engelman, M.D., Ph.D., Harvard Medical School, Boston, MA Michael W. Deininger, M.D., Ph.D., University of Utah, Salt Lake City, UT

Register Now