FC-L
H
Endogenous
Rabbit IgG
#Q9NP99
54210
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Flow Cytometry (Live) | 1:50 |
Storage
Specificity / Sensitivity
Species Reactivity:
Human
Source / Purification
Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the extracellular domain of human TREM1 protein.
Background
The triggering receptor expressed on myeloid cells 1 (TREM1) protein is an innate immune receptor that is primarily expressed on the cell surface of myeloid cells (1). TREM1 is a single-pass type I membrane glycoprotein that consists of an extracellular immunoglobulin-like domain, a transmembrane domain, and a cytoplasmic tail. TREM1, like its related protein TREM2, interacts with the tyrosine kinase-binding protein DAP12 to form a receptor-signaling complex (2). By accepting a diverse array of ligands, TREM1-expressing macrophages and neutrophils modulate inflammation through cytokine, chemokine, and receptor upregulation (2,3).
Species Reactivity
Species reactivity is determined by testing in at least one approved application (e.g., western blot).
Applications Key
FC-L: Flow Cytometry (Live)
Cross-Reactivity Key
H: human M: mouse R: rat Hm: hamster Mk: monkey Vir: virus Mi: mink C: chicken Dm: D. melanogaster X: Xenopus Z: zebrafish B: bovine Dg: dog Pg: pig Sc: S. cerevisiae Ce: C. elegans Hr: horse GP: Guinea Pig Rab: rabbit All: all species expected
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