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Flow Cytometry

Flow Cytometry

Traditionally, flow cytometry has been used to identify distinct cell types within a heterogeneous pool of cells, based on extracellular or surface marker expression, an application commonly known as immuno-phenotyping. However, this technology is also readily amenable to intracellular target detection and can be successfully applied to the study of complex signaling events.

Thus combined with the detection of cell surface markers intracellular flow cytometry has evolved into a powerful platform, which enables characterization of signaling networks at a single cell level within phenotypically distinct cell populations.