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RNA Regulation and Translational Control

RNA Regulation and Translational Control

Gene expression is modulated by post-transcriptional and translational control to regulate a variety of cellular processes, including development, cell differentiation, and metabolism. Post-transcriptional modifications and processing of messenger RNA (mRNA) regulates abundance and localization of mRNA molecules as well as downstream translation of mRNA to protein. The RNA life cycle is regulated by a multitude of RNA Binding proteins (RBPs) which are vital to ensure accurate and basic gene expression. Dysregulation of these RBPs and processes can result in a host of human diseases, such as cancer, neurodegenerative diseases including Alzheimer’s disease, spinal muscular atrophy, Amyotrophic Lateral Sclerosis (ALS), and autoimmune disorders. Partner with Cell Signaling Technology (CST) to obtain high-quality data through antibodies that examine RBPs and RNA modifications, in support of research toward understanding the processes governing the RNA life cycle.