Mass spectrometry techniques can be used to profile post-translationally modified (PTM) digested peptides from a sample, although some type of enrichment is typically needed since they generally exist in low abundance. Cell Signaling Technology® (CST™) developed PTMScan, a proprietary proteomic technology that couples antibody enrichment of PTM-containing peptides with liquid chromatograpy mass spectromety (LC-MS/MS), allowing for the identification and quantification of hundreds to thousands of low abundance PTM peptides. We have compiled a collection of videos, app notes, eBook, blogs and more to demonstrate the power of PTMScan and the many ways you can utilize it in your research.
