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Neuroinflammation is a condition observed in the central nervous system (CNS) in response to infection, toxic metabolites, traumatic injury, or autoimmunity.
Identify microglia by using these antibodies, which are designed to detect protein biomarkers specifically expressed within these cells.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
The Inflammasome pathway is essential for the innate immune response, but it can also contribute to the onset of a number of diseases. Learn more here.
Pyroptosis is a type of programmed necrotic cell death activated by infections from bacteria, viruses, fungi or protozoa in the presence of PAMPs or DAMPs
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
Regulation of cell death due to viral infection is important for host survival. In this series, we look at pathways regulated through cellular responses to viruses.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Cancer cells hijack inflammatory mechanisms to promote their own growth and survival.
The regulation of ER stress and autophagy during viral infection is an important factor in the balance of virus and host survival.
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
These markers can be used to study necroptosis and pyroptosis, forms of regulated necrotic cell death that share morphological features with necrosis.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Here’s what you should know about your target before you start searching for antibodies, and the questions to ask to avoid choosing the wrong one.
A scientific resource for the SH2 protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
Frequently asked questions using our products while doing your research
Knowing how antibodies and immunoassays have evolved as research tools can help you design more robust, reproducible scientific experiments.
CUT&RUN Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
CUT&Tag Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
Writing an abstract — condensing your information into 200 words — is daunting. This post outlines the steps to draft an abstract tailored to the journal you want.
Chromatin IP (ChIP) Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
What makes an antibody monoclonal, polyclonal, or recombinant? Is one better than the other, or are they all designed for different purposes?
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Learn about the power and applications of recombinant antibodies in research. Click here to find out more and revolutionize your experiments.
Tamar Aprahamian is an interesting study in the professional opportunities available for young scientists. She's worked in academia, industry, and most recently has co-founded a company of science writers called JetPub. She has been a contributor to our blog and was nice enough to share her story.
What antibodies can be used in a CUT&RUN protocol? What controls should be included to measure signal-to-noise? These and other frequently asked questions are answered in this edition of CST Tech Tips.
