There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Fluorescent multiplex IHC (mIHC) with tyramide signal amplification enables simultaneous detection of multiple proteins in formalin-fixed paraffin-embedded (FFPE) tissue sections in a sequential fashion.
A broad range of techniques are used to study neurodegenerative diseases including basic cellular and molecular protocols, ELISA, electrophysiological assessments, and imaging-based methods that utilize antibody-based technology.
Neuroinflammation is the activation of an immune response in the CNS by the microglia and astrocytes. While not linked mechanistically to neurodegenerative diseases, neuroinflammation is associated with the progression of Alzheimer's disease, Parkinson's
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.