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When it comes to mouse tissue samples, not all loading control proteins are expressed equally. Learn which control is right for your research.
CUT&RUN is a revolutionary technique that lets you see DNA-protein interactions in a whole new way. Identify protein binding sites at high resolution. Click
Loading controls are essential to ensure data reliability in your western blot. Learn about the three main considerations for loading control selection.
Learn how CUT&Tag cuts down your chromatin profiling experiment time. You’ll get the same great data with a fraction of the DNA library prep time and improved signal-to-noise.
Loading control proteins are often more abundant than the protein of interest, which can lead to the signal exceeding the linear dynamic range of detection
CUT&Tag Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
Ensure equal sample loading with loading control antibodies from CST.
CUT&RUN Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
The benefits of using micrococcal nuclease to digest chromatin compared to sonication.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
As a new antibody is developed, Cell Signaling Technology scientists test the antibody’s stability and activity
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
This is a four-part series featuring tips to improve your ChIP protocol.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Maximize your research with our CUT&RUN Kit. Streamline chromatin profiling with our efficient, user-friendly tools designed for deeper, more insightful analyses.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
CST antibodies undergo rigorous stability testing to ensure quality. To reduce our carbon footprint, cold shipping is used only when necessary.
Chromatin immunoprecipitation, or ChIP, is a technique that uses antibodies to isolate specific DNA-binding proteins along with the bound DNA fragments from cells and tissues.
Apoptosis is a type of programmed cell death that occurs normally throughout the lifespan and can also occur in response to harmful stimuli. Apoptotic cells are identified by their altered morphology, caspase activation, and the presence of damaged DNA.
Chromatin IP (ChIP) Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
A binary approach is one of the best ways to evaluate antibody specificity. By testing an antibody in biologically relevant positive and negative expression systems.
A binary approach is one of the best ways to evaluate antibody specificity.
CUT&Tag delivers quality NGS data even if the signal from the Bioanalyzer or TapeStation System is low and the DNA library yield is low.
The Akt Binding Partners Table provides a list of proteins that bind to Akt along with their effects, activities, and corresponding PubMed reference(s).
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
SimpleChIP® Plus Sonication Chromatin Immunoprecipitation Protocol (Magnetic Beads): easy to follow directions describing the step by step experimental procedure
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Fostering mentorship, application-based learning, and a love of science are all part of the mission of the CST internship program. Students interning with us are partnered with CST Mentors.
