A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
A scientific resource for the 14-3-3 protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
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Flow Cytometry is readily amenable to intracellular target detection and can be successfully applied to the study of complex signaling pathways
An antibody shouldn’t be one of the variables in your experiment. Find out why customers rank CST highest for antibody specificity and sensitivity.
Explore our journey from radioactive labeling to pioneering antibody technology, all while maintaining a commitment to corporate social responsibility.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Will an antibody validated for WB perform as expected in an IF experiment? Here, we compare an IF-validated mAb from CST to one from another vendor.
Lymphoid lineage cells can be characterized using antibodies for cell type-specific markers, allowing cells to be visualized using flow cytometry or IHC.
CST Blog: Hear from our researchers about the latest antibody tools and technology, as well as tips and tricks for reproducible, responsible science.
Learn about the power and applications of recombinant antibodies in research. Click here to find out more and revolutionize your experiments.
PTMScan Motif Antibody Kits from Cell Signaling Technology
Expert-reviewed interactive pathway providing a current overview of the Warburg Effect.
Immunohistochemistry application information
Discover the TGF Beta signaling pathway and impact on cell growth & tissue homeostasis. Learn here the mechanisms behind this vital signaling cascade.
CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
Expert-reviewed interactive pathway providing a current overview of the molecular and cellular biology of Alzheimer’s Disease.
Expert-reviewed diagram providing a current overview of the Senescence Signaling pathway with references to its role in cell cycle
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
Mitophagy is a well-studied example of selective autophagy. This post explores mitophagy functions and the consequence of excessive or inadequate mitophagy
Learn about BCR signaling and how it can lead to changes in cell metabolism, gene expression, and cytoskeletal organization. Click here.
