Multiplex IHC - Being able to visualize multiple targets simultaneously is important in research fields like immunology & oncology. Learn more here.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Flow Cytometry is readily amenable to intracellular target detection and can be successfully applied to the study of complex signaling pathways
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
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Will an antibody validated for WB perform as expected in an IF experiment? Here, we compare an IF-validated mAb from CST to one from another vendor.
The volume of material varies between vials of the MitoTracker® products because of the small volume of the reagent added to the vial. When these vials dry, there can be localized vapor pressures that affect how the residue pellets out.
IHC-F can refer to several different protocols in different sample types. Tissue that is formalin fixed and paraffin embedded is used with dye-conjugated antibodies and this can be IHC-F.
CST Blog: Hear from our researchers about the latest antibody tools and technology, as well as tips and tricks for reproducible, responsible science.
The concentration of our Glycine Solution (10X) #7005 is 1.25M and the pH is 6.5.
The concentration of our Digitonin Solution #16359 is proprietary. The concentration will vary between lots, as we internally test each lot to match performance before release.
RRIDs (Research Resource Identifiers) can be found in the RRID Portal (https://scicrunch.org/resources). Simply search for the product number (excluding letters), clone number, or target along with 'Cell Signaling Technology'.
Lymphoid lineage cells can be characterized using antibodies for cell type-specific markers, allowing cells to be visualized using flow cytometry or IHC.
Explore our journey from radioactive labeling to pioneering antibody technology, all while maintaining a commitment to corporate social responsibility.
The TGF-β Antibody #3711 detects recombinant TGF-β1, TGF-β2, and TGF-β3. The antibody also detects endogenous levels of the TGF-β1 precursor proteins.
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How does ChIP-Seq work? This powerful technique combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions. Learn more.
Dr. David Rimm of Yale School of Medicine discusses multiplexing spatial imaging technologies and their development to improve response prediction for immunotherapy. This webinar was recorded at AACR 2022.
U.S. Patent No. 6,441,140, directed to the production of a novel class of motif-specific, context-independent antibodies, highly useful for the identification of subclasses of protein kinase substrates.
An antibody shouldn’t be one of the variables in your experiment. Find out why customers rank CST highest for antibody specificity and sensitivity.
Fill out the form to contact the Proteomics Analytical Services team.
Webinar featuring Reuben Shaw, Professor at the Molecular and Cell Biology Laboratory, Deputy Director of Salk Cancer Center, Salk Institute for Biological Studies.
A scientific resource for the 14-3-3 protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
Measuring and comparing cell viability in your assays is important, whether it’s the data you’re pursuing or an important control in your experiment.
