Custom synthesized, isotope-labeled AQUA peptides for validating and quantifying protein markers and post-translational modifications from Cell Signaling Technology.
Synopsis of CST scientists' publication in the journal Science Signaling describing phosphorylation patterns associated with non-small cell lung cancer (NSCLC).
Overview of PTMScan technology for proteomics from CST. Antibody enrichment of PTM peptides combined with mass spectrometry.
A listing of PTMScan Motif Antibodies and Kits, along with case study data for each, for customers who purchase a license and would like to perform PTMScan Proteomics in-house.
A table that lists shelf-life expectations for CST products (when stored under the recommended conditions).
PTMScan proteomics services. Antibody enrichment of PTM peptides combined with mass spectrometry
CST sponsored Science Webinar Series: Exploring Cell Signaling through Mass Spec: May 1, 2013. Hear the webinar (3 speakers), download slides and transcripts.
PTMScan® Discovery proteomics technology – antibody enrichment for LC-MS/MS
PTMScan® Motif Antibody Kits from Cell Signaling Technology
Features, benefits, and product listing for PTMScan Direct Proteomic Services for the targeted screening of defined protein sites critical for drug and biomarker discovery.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST, which allows for targeted screening of 100 proteins within defined pathways.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST, which allows for targeted screening of 263 proteins within defined pathways.
Information and case study data for the PTMScan Direct Multi-Pathway Service, which allows targeted screening of defined protein sites within multiple signaling pathways.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein sites within the Ser/Thr kinome.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service, which allows for the targeted screening of a defined set of protein sites within the tyrosine kinome.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).