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Cigall Kadoch, PhD: Specific, High Affinity Antibodies for Discovery


As the importance of the mammalian SWI/SNF (BAF) complexes in contributing to cancer became apparent, Cigall Kadoch PhD realized there was a real lack of reagents to effectively study this class of proteins. So, her lab teamed up with Cell Signaling Technology to drive the development of new antibodies. In this video, Dr. Kadoch describes an exciting project that overcame a long-standing challenge: the development of a specific antibody to study the SS18-SSX fusion oncoprotein.