Exceptional Specificity of XP® Monoclonal Antibodies

Antibodies directed against phosphorylated proteins often cross-react with related proteins, resulting in cross-reacting bands or a false positive signal. We compared two XP® monoclonal antibodies, Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb #4370 and Phospho-Met (Tyr1234/1235) (D26) XP® Rabbit mAb #3077, to competing products in a number of relevant research applications.