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Cell Signaling Technology and Leica Biosystems Partner to Enable Companion Diagnostic (CDx) Development

Danvers, MA and San Diego, CA - September 6, 2023

Cell Signaling Technology (CST), a life science discovery technology company and leading provider of antibodies, kits, and services, is partnered with Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, to support the development of companion diagnostics (CDx) assays using the extensive portfolio of best-in-class antibodies from CST validated for immunohistochemistry (IHC). Leica is a global market leader in enabling the translation of pre-clinical research into CDx tests, helping pharma partners develop and commercialize cutting-edge diagnostic solutions to identify patients likely to benefit from emerging therapeutics.

Clinical trial recruitment and assessment of patient biomarker status are dependent on the use of effective and reliable CDx assays as a critical component of guiding treatment decisions for personalized medicine. Since 2020, this agreement has facilitated the use of trusted CST® antibodies to unique biomarkers by the Leica Biosystems CDx team to enable leading biotechnology and pharmaceutical companies to leverage these fit-for-purpose tools to support the drug development workflow. 

“Ensuring the availability of trusted, highly validated antibody products from initial discovery through translation and CDx development streamlines the pharmaceutical development process and de-risks product commercialization,” said Roberto Polakiewicz, Chief Scientific Officer at CST. “Strategic partnerships like this help drive precision medicine forward by enabling more rapid and efficient development of new therapies to devastating diseases. We're excited to continue working with Leica's leading CDx team to support the advancement of biotherapeutics from discovery through to the clinic.”

“Since the establishment of our Companion Diagnostics Team in 2012, our expertise in immunohistochemistry, in situ hybridization, and automation has enabled assay development for a diverse range of biomarker targets across a variety of cancer types for our Biopharma partners,” said Rob Monroe, Chief Medical Officer at Leica Biosystems. “We are excited to collaborate with CST to develop transformative companion diagnostics for the advancement of personalized medicine for cancer patients.”

CST was named Antibody Supplier of the Decade and the 2022 Supplier Succeeding in Cancer Research by CiteAb due to the company's commitment to rigorous validation standards, strong scientific foundation, and ever-expanding portfolio of antibody reagents to unique biomarkers. Across the industry, CST antibodies are trusted for their sensitivity, specificity, and reproducible performance in the assays in which they are validated.

Learn more about Leica CDx at:

The license agreement between Leica Biosystems and CST has existed since 2020.

About Leica Biosystems

Leica Biosystems is a global leader in workflow solutions and automation. As the only company to own the workflow from biopsy to diagnosis, they are uniquely positioned to break down the barriers between each of these steps. Leica Biosystems' mission of “Advancing Cancer Diagnostics, Improving Lives” is at the heart of their corporate culture. Their easy-to-use and consistently reliable offerings help improve workflow efficiency and diagnostic confidence. The company is represented in over 100 countries. It has manufacturing facilities in 9 countries, sales and service organizations in 19 countries, and an international network of dealers. The company is headquartered in Nussloch, Germany. Visit for more information.

About Cell Signaling Technology

Cell Signaling Technology (CST) is a different kind of life science company—one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor. Founded in 1999 and headquartered in Danvers, Massachusetts, USA, CST employs over 600 people worldwide. We consistently provide fellow scientists around the globe with best-in-class products and services to fuel their quests for discovery. CST is a company of caring people driven by a devotion to facilitating good science—a company committed to doing the right thing for our Customers, our communities, and our planet.

Leica Biosystems Corporate Communications

Lauren Meinhardt
Phone: 657-226-6970
email: [email protected]

CST Media and Press

Rebecca J. Reppucci, MBA
Cell Signaling Technology, Inc.
Senior Director, Global MarComm & Technology
Phone: 978-880-3334
email: [email protected]