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News From the Bench

News from the Bench

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National Harbor, MD – November 4, 2015 – Cell Signaling Technology, Inc. (CST), a worldwide provider of antibodies, announced today the release of 6 new monoclonal antibodies (mAb) for tumor immunology research. This announcement was made at the 30th annual meeting of the Society for Immunotherapy of Cancer (SITC) at National Harbor, MD November 4-8th, 2015.

CST has released PD-L2 (D7U8C) XP® Rabbit mAb #82723, PD-L1 (Extracellular Domain Specific) (E1J2J) Rabbit mAb #15165, PD-L1 (405.9A11) Mouse mAb #29122, PD-1 (EH33) Mouse mAb #43248, TIM-3 (D5D5R) XP® Rabbit mAb #45208, and IDO (D5J4E) Rabbit mAb #86630. Each of these antibodies has been validated according to CST’s stringent standards to recognize their specific immune regulatory target by immunohistochemistry.

These antibodies add to a growing portfolio of tumor immunology products that includes the first to market, human-specific, IHC-approved VISTA (D1L2G™) XP® Rabbit mAb #64953, as well as PD-L1 (E1L3N®) XP® Rabbit mAb #13684, PD-1 (D3W4U) Rabbit mAb #15121, CTLA-4 (D4E9I) Rabbit mAb #15119, OX40 (D1S6L) Rabbit mAb #15123, B7-H3 (D9M2L) XP® Rabbit mAb #14058, and B7-H4 (D1M8I) XP® Rabbit mAb #14572.

Today’s announcement follows the October 6th, 2015 announcement that CST’s best-in-class recombinant rabbit monoclonal antibodies, developed with their proprietary XMT® and NG-XMT™ technologies can now be manufactured according to FDA (Food and Drug Administration) GMP (Good Manufacturing Practices) requirements for Analyte Specific Reagents.

“The release of these products reflects our continued commitment to provide complete turnkey solutions to the tumor immunology community. Moreover, our ability to manufacture GMP-grade antibodies puts us in a position to support translational tumor immunology research, from project conception through to clinical application. This has the potential to facilitate translational assay development and simplify the bench to bedside transition,” said Michael J. Comb, CEO of CST.

About CST

Cell Signaling Technology (CST) is a private, family-owned company, founded by scientists and dedicated to providing the world’s highest quality, innovative, research and diagnostic products to accelerate biological understanding and enable personalized medicine. Our employees operate worldwide from our U.S. headquarters in Massachusetts, and our offices in the Netherlands, China, and Japan.

XP®, XMT®, NG-XMT™, D1L2G™, E1L3N®, Cell Signaling Technology®, and CST™ are trademarks of Cell Signaling Technology, Inc.


Rebecca J. Reppucci, MBA
Cell Signaling Technology, Inc.
Director of Marketing Communications
Phone: 978-867-2382