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Dexras1 Antibody #4229

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  • WB

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 30
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Dexras1 Antibody detects endogenous levels of total Dexras1 protein. This antibody also cross-reacts with a 60 kDa protein of unknown origin.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Dexras1 protein. Antibodies were purified by protein A and peptide affinity chromatography.

    Background

    Dexras1 (Ras dexamethasone induced 1) belongs to the Ras superfamily of GTPases and was initially identified as a dexamethasone inducible gene (1,2). Dexras1 reportedly regulates several distinct signal transduction pathways, including MAPK signaling, NMDA receptor-nitric oxide-mediated signaling, and pathways involving adenylyl cyclases (3-5). Dexras1 can directly modulate FE65-APP-mediated transcription and regulate the photic sensitivity of the mammalian circadian clock (6,7).

    Alternate Names

    activator of G protein signaling; Activator of G-protein signaling 1; AGS1; Dexamethasone-induced Ras-related protein 1; DEXRAS1; MGC:26290; ras related dexamethasone induced 1; ras-related protein; RAS, dexamethasone-induced 1; RASD1

    For Research Use Only. Not for Use in Diagnostic Procedures.
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