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Camostat Mesylate
Activators & Inhibitors
Chemical Modulators

Camostat Mesylate #42819

Citations (0)
Chemical structure of Camostat Mesylate.

Product Usage Information

Camostat Mesylate is supplied as a lyophilized powder. For a 15 mM stock, reconstitute 10 mg of powder in 1.34 ml of DMSO. Working concentrations and length of treatment can vary depending on the desired effect.


Store lyophilized at -20ºC, desiccated. In lyophilized form, the chemical is stable for 24 months. Once in solution, store at -20ºC and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Description

Molecular Weight 494.5 g/mol
Purity >98%
Molecular Formula C20H22N4O5 • CH3SO3H
CAS 59721-29-8
Solubility Soluble in DMSO at 50 mg/ml or water at 50 mg/ml.


Camostat Mesylate, also known as Foipan or FOY 305, is a synthetic serine protease inhibitor that is often used to treat pancreatitis pain (1). Camostat Mesylate attenuates airway epithelial sodium channel (ENaC) function by inhibiting channel-activating proteases (CAPs) with an IC50 of 50 nM (2). Camostat Mesylate inhibition of trypsin decreased food intake, body weight, blood glucose, liver weight, and lipidosis and increased FGF21 expression in obese mice (3).

Camostat Mesylate is an effective inhibitor of TMPRSS2, a serine protease used by SARS-CoV-2/COVID-19 for viral S-protein priming and cell entry. Pre-treatment of human lung cancer cells with 100 μM Camostat Mesylate significantly reduced COVID-19 viral entry (4).

Limited Uses

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Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.

For Research Use Only. Not for Use in Diagnostic Procedures.
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To Purchase # 42819
Cat. # Size Qty. Price
10 mg