BAD Antibodies

Target Information

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. Belongs to the Bcl-2 family. Expressed in a wide variety of tissues. Note: This description may include information from UniProtKB.

Alternate Names

AI325008; BAD; BBC2; Bbc2; BBC6; Bbc6; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl-associated death promoter; BCL-X/BCL-2 binding protein; Bcl-XL/Bcl-2-associated death promoter; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; BCL2-antagonist of cell death protein; Bcl2-associated agonist of cell death; BCL2-binding component 6; BCL2-binding protein; Bcl2-L-8; BCL2L8; OTTMUSP00000017561