HMOX1 Antibodies

Target Information

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. Belongs to the heme oxygenase family. Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). Note: This description may include information from UniProtKB.

Alternate Names