HSP27 Antibodies

Target Information

Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Belongs to the small heat shock protein (HSP20) family. Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle. Note: This description may include information from UniProtKB.

Alternate Names

27kDa; 28 kDa heat shock protein; CMT2F; DKFZp586P1322; epididymis secretory protein Li 102; Estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; Heat shock 25 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; heat shock protein 1; Heat shock protein beta-1; heat shock protein family B (small) member 1; heat shock protein, 25 kDa; HEL-S-102; HMN2B; HS.76067; Hsp; HSP 25; HSP 27; Hsp25; HSP27; Hsp27; HSP28; HSPB1; HspB1; OTTMUSP00000028918; p25; SRP27; Stress-responsive protein 27; truncated hsp25