IFNAR2 Antibodies

Target Information

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. Belongs to the type II cytokine receptor family. Isoform 3 is detected in the urine (at protein level) (PubMed:8181059, PubMed:7759950). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AI747302; human interferon alpha/beta receptor; Ifn; IFN-alpha binding protein; IFN-alpha-REC; IFN-alpha/beta receptor 2; IFN-R; IFN-R-2; IFNABR; Ifnar-2; IFNAR2; Ifnar2; IFNARB; IMD45; INAR2; interferon (alpha and beta) receptor 2; interferon (alpha, beta and omega) receptor 2; interferon alpha and beta receptor subunit 2; Interferon alpha binding protein; Interferon alpha/beta receptor 2; interferon receptor; interferon receptor 2a'; interferon receptor 2c; interferon-alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon alpha/beta receptor 2a; Type I interferon receptor 2