KIF5B Antibodies
Target Information
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily. Note: This description may include information from UniProtKB.
Alternate Names
Conventional kinesin heavy chain; epididymis secretory protein Li 61; HEL-S-61; KIF5B; kinesin 1 (110-120kD); kinesin family member 5B; kinesin heavy chain; Kinesin-1 heavy chain; KINH; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHCKIF5B Antibody Products
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