MCM4 Antibodies

Target Information

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Belongs to the MCM family. Note: This description may include information from UniProtKB.

Alternate Names

CDC21; CDC21 homolog; CDC54; DNA replication licensing factor MCM4; hCdc21; homolog of S. pombe cell devision cycle 21; IMD54; MCM4; MCM4 minichromosome maintenance deficient 4; MGC33310; minichromosome maintenance complex component 4; minichromosome maintenance deficient 4; NKCD; NKGCD; P1-CDC21