PHOX2B Antibodies

Target Information

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. Belongs to the paired homeobox family. Expressed in neuroblastoma, brain and adrenal gland. Note: This description may include information from UniProtKB.

Alternate Names

CCHS; NBLST2; NBPhox; neuroblastoma paired-type homeobox protein; Neuroblastoma Phox; paired like homeobox 2B; paired like homeobox2B; paired mesoderm homeobox 2b; Paired mesoderm homeobox protein 2B; Paired-like homeobox 2B; PHOX2B; PHOX2B homeodomain protein; PHX2B; PMX2B