PSD-93 Antibodies

Target Information

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. Belongs to the MAGUK family. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

Channel-associated protein of synapse-110; channel-associated protein of synapses, 110kDa; Chapsyn-110; discs large MAGUK scaffold protein 2; discs, large homolog 2 (Drosophila); discs, large homolog 2, chapsyn-110; Disks large homolog 2; DKFZp781D1854; DKFZp781E0954; DLG2; FLJ37266; MGC131811; Postsynaptic density protein PSD-93; PPP1R58; protein phosphatase 1, regulatory subunit 58; PSD-93; PSD93