SETD3 Antibodies

Target Information

Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD3 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

Actin-histidine N-methyltransferase; C14orf154; DKFZp761E1415; FLJ23027; Histone-lysine N-methyltransferase setd3; hSETD3; MGC87236; SET domain containing 3; SET domain containing 3, actin histidine methyltransferase; SET domain-containing protein 3; SETD3