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SPIB Antibodies

You can find the right SPIB antibody for your scientific research with our 2 antibodies developed in Rabbit. These antibodies are validated for detecting SPIB in Human and Mouse samples using techniques like Immunoprecipitation, Flow Cytometry (Fixed/Permeabilized), Immunofluorescence (Immunocytochemistry) and Western Blotting. Our SPIB antibodies have been cited in 8 publications and have 7 product images.

Target Information

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation. Belongs to the ETS family. Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

SPI-B; Spi-B transcription factor; Spi-B transcription factor (Spi-1/PU.1 related); SPIB; Transcription factor Spi-B

SPIB Antibody Products

2 Products
Product #
Product Name
Applications
Reactivity
Clonality
1-2 of 2
Application Key:
WB - Western
IHC - Immunohistochemistry
IF - Immunofluorescence
F - Flow Cytometry
ChIP - Chromatin Immunoprecipitation
ELISA+ - ELISA and/or ELISA-like Assays
Species Cross-Reactivity Key:
H-Human M-Mouse R-Rat Hm-Hamster Mk-Monkey Vir-Virus Mi-Mink C-Chicken Dm-D. melanogaster X-Xenopus Z-Zebrafish B-Bovine Dg-Dog Pg-Pig Sc-S. cerevisiae Ce-C. elegans Hr-Horse GP-Guinea Pig Rab-Rabbit All-All Species Expected

Why CST

Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:

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