TRAIL Antibodies

Target Information

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Belongs to the tumor necrosis factor family. Widespread; most predominant in spleen, lung and prostate. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

A330042I21Rik; AI448571; Apo-2 ligand; APO-2L; Apo-2L; APO2L; CD253; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; TNF10; TNFSF10; Tnfsf10; TNLG6A; Tnlg6a; TRAIL; Trail; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand 6a; Tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10