Cell Signaling Technology Logo - Extra Large

VHL Antibodies

You can find the right VHL antibody for your scientific research with our 6 antibodies developed in Rabbit. These antibodies are validated for detecting VHL in Human and Mouse samples using techniques like ELISA+, IHC Leica Bond, Immunohistochemistry (Paraffin), Simple Western™, Peptide ELISA (DELFIA) and Western Blotting. Our VHL antibodies have been cited in 132 publications and have 36 product images.

Target Information

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. Belongs to the VHL family. Expressed in the adult and fetal brain and kidney. 3 alternative splicing and alternative initiation human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau tumor suppressor; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

VHL Antibody Products

6 Products
Product #
Product Name
Applications
Reactivity
Clonality

1-6 of 6
Application Key:
WB - Western
IHC - Immunohistochemistry
IF - Immunofluorescence
F - Flow Cytometry
ChIP - Chromatin Immunoprecipitation
ELISA+ - ELISA and/or ELISA-like Assays
Species Cross-Reactivity Key:
H-Human M-Mouse R-Rat Hm-Hamster Mk-Monkey Vir-Virus Mi-Mink C-Chicken Dm-D. melanogaster X-Xenopus Z-Zebrafish B-Bovine Dg-Dog Pg-Pig Sc-S. cerevisiae Ce-C. elegans Hr-Horse GP-Guinea Pig Rab-Rabbit All-All Species Expected

Why CST

Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:

Contact

Don’t see an antibody for your specific needs? Browse more products, learn more about our services or get in touch with us: