WNT3A Antibodies

Target Information

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube. Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro). Belongs to the Wnt family. Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names