AGO1 Antibodies

Target Information

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). Belongs to the argonaute family. Ago subfamily. Note: This description may include information from UniProtKB.

Alternate Names

AGO1; argonaute 1; argonaute 1, RISC catalytic component; Argonaute RISC catalytic component 1; argonaute RISC component 1; Argonaute1; DKFZp686M13167; eIF-2C 1; EIF2C; eIF2C 1; EIF2C1; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; Protein argonaute-1; Putative RNA-binding protein Q99; Q99