ATAD2 Antibodies

Target Information

May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. Belongs to the AAA ATPase family. Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AAA nuclear coregulator cancer-associated protein; ANCCA; ATAD2; ATPase family AAA domain containing 2; ATPase family AAA domain-containing protein 2; ATPase family, AAA domain containing 2; CT137; DKFZp667N1320; MGC131938; MGC142216; MGC29843; MGC5254; PRO2000