CBP Antibodies
Target Information
Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER). Functions as a transcriptional coactivator for SMAD4 in the TGF-beta signaling pathway. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
CBP; CREB binding protein; CREB-binding protein; CREBBP; Histone lysine acetyltransferase CREBBP; KAT3A; MKHK1; Protein-lysine acetyltransferase CREBBP; RSTS; RSTS1CBP Antibody Products
4 Products- 63794WBIFH, M, R, MkRecombinant Monoclonal
Why CST
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