CCL2 Antibodies

Target Information

Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Belongs to the intercrine beta (chemokine CC) family. Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level) (PubMed:23765988). Expressed in monocytes (PubMed:2513477). Note: This description may include information from UniProtKB.

Alternate Names

AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; CCL2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; HSMCR30; Je; MCAF; MCP; MCP-1; MCP1; Mcp1; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; OTTMUSP00000000786; Platelet-derived growth factor-inducible protein JE; SCYA2; Scya2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; Small-inducible cytokine A2; SMC-CF