EIF4E Antibodies

Target Information

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. Belongs to the eukaryotic initiation factor 4E family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AUTS19; CBP; EG668879; eIF-4; eIF-4E; eIF-4F 25 kDa subunit; EIF4E; Eif4e; Eif4e-ps; EIF4E1; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; If4; IF4E; If4e; MGC103177; MGC111573; mRNA cap-binding protein