FCGRT Antibodies

Target Information

Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily. Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine. Note: This description may include information from UniProtKB.

Alternate Names

alpha-chain; Fc fragment of IgG receptor and transporter; Fc fragment of IgG, receptor, transporter, alpha; Fc receptor, IgG, alpha chain transporter; FCGRN; FCGRT; Fcgrt; FCRN; FcRn; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; igG Fc fragment receptor transporter alpha; IgG Fc fragment receptor transporter alpha chain; IgG Fc receptor; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc receptor; neonatal Fc-receptor for Ig; Q61559; transmembrane alpha chain of the neonatal receptor