FOLR1 Antibodies
Target Information
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Belongs to the folate receptor family. Primarily expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum. Detected in placenta and thymus epithelium. Note: This description may include information from UniProtKB.
Alternate Names
Adult folate-binding protein; FBP; folate binding protein; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor, adult; FOLR; FOLR1; FR-alpha; FRalpha; KB cells FBP; Ovarian tumor-associated antigen MOv18FOLR1 Antibody Products
4 Products- 30124WBIHCH, MMonoclonal
- 53873IHCH, MMonoclonal
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