GZMH Antibodies

Target Information

Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. Belongs to the peptidase S1 family. Granzyme subfamily. Constitutively expressed in NK cells. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AKA granzyme G; C134; Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP; CCP-X; CCP4; CGL-2; CGL2; CSP-C; Ctl; CTL serine protease 3; Ctla; Ctla-7; CTLA1; Ctla7; CTSGL2; Cytotoxic cell protease 4; Cytotoxic serine protease 3; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; GRAF; GRAH; Granzyme F; granzyme G; Granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); Gzmf; GZMH; MCSP; MCSP-3; MCSP3