H2AX Antibodies
Target Information
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. Belongs to the histone H2A family. Note: This description may include information from UniProtKB.
Alternate Names
H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2a/x; H2AFX; H2AX; H2AX histone; Histone H2A.x; Histone H2AXH2AX Antibody Products
31 Products- 9718WBIHCIFFH, M, R, MkRecombinant Monoclonal
- 80312WBIHCIFFH, M, R, MkRecombinant Monoclonal
- 9719FH, M, R, MkRecombinant Monoclonal
- 9720FH, M, R, MkRecombinant Monoclonal
- 60566WBIHCIFFH, M, R, MkRecombinant Monoclonal
- 5763FH, M, R, MkRecombinant Monoclonal
- 97148WBIHCIFFH, M, R, MkMonoclonal
- 20304FH, M, R, MkMonoclonal
- 81330FH, M, R, MkMonoclonal
- 59141FH, M, R, MkRecombinant Monoclonal
- 47907FH, M, R, MkRecombinant Monoclonal
- 85410FH, M, R, MkMonoclonal
- 4309WBELISA+H, M, R, MkRecombinant Monoclonal
- 49236FH, M, R, MkRecombinant Monoclonal
- 93629FH, M, R, MkMonoclonal
- 53604FH, M, R, MkRecombinant Monoclonal
- 24433FH, M, R, MkRecombinant Monoclonal
- 80649H, M, R, MkRecombinant Monoclonal
- 54937WBH, M, R, MkRecombinant Monoclonal
- 24533WBIHCIFFELISA+H, M, R, MkRecombinant Monoclonal
- 48325H, M, R, MkRecombinant Monoclonal
- 31329H, M, R, MkRecombinant Monoclonal
- 39711H, M, R, MkRecombinant Monoclonal
- 96512H, M, R, MkRecombinant Monoclonal
- 92853H, MRecombinant Monoclonal
- 44274WBELISA+H, MMonoclonal
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