HAT1 Antibodies
Target Information
Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage. Belongs to the HAT1 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
HAT1; histone acetyltransferase 1; Histone acetyltransferase type B catalytic subunit; KAT1HAT1 Antibody Products
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