Cell Signaling Technology Logo - Extra Large
View Featured Offers >>
  1. Home /
  2. Products /
  3. Antibodies /
  4. Notch 2

Notch 2 Antibodies

You can find the right Notch 2 antibody for your scientific research with our 7 antibodies developed in Rabbit. These antibodies are validated for detecting Notch 2 in Human, Mouse and Rat samples using techniques like Immunofluorescence (Immunocytochemistry), Flow Cytometry (Fixed/Permeabilized), Western Blotting, Immunoprecipitation, Immunohistochemistry (Paraffin), IHC Leica Bond and Single Cell Analysis - InTraSeq™ 3'. Our Notch 2 antibodies have been cited in 233 publications and have 37 product images.

Target Information

Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells. Belongs to the NOTCH family. Expressed in the brain, heart, kidney, lung, skeletal muscle and liver. Ubiquitously expressed in the embryo. Note: This description may include information from UniProtKB.

Alternate Names

AGS2; HJCYS; hN2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; NOTC2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; Notch homolog 2; Notch homolog 2 (Drosophila); notch receptor 2; NOTCH2

Notch 2 Antibody Products

7 Products
Product #
Product Name
Applications
Reactivity
Clonality
1-7 of 7
Application Key:
WB - Western
IHC - Immunohistochemistry
IF - Immunofluorescence
F - Flow Cytometry
ChIP - Chromatin Immunoprecipitation
ELISA+ - ELISA and/or ELISA-like Assays
Species Cross-Reactivity Key:
H-Human M-Mouse R-Rat Hm-Hamster Mk-Monkey Vir-Virus Mi-Mink C-Chicken Dm-D. melanogaster X-Xenopus Z-Zebrafish B-Bovine Dg-Dog Pg-Pig Sc-S. cerevisiae Ce-C. elegans Hr-Horse GP-Guinea Pig Rab-Rabbit All-All Species Expected

Why CST

Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:

Our Approach/Process Product Performance Guarantee Our Tech Support Promise

Contact

Don’t see an antibody for your specific needs? Browse more products, learn more about our services or get in touch with us:

Browse All Products Custom Conjugation Services Contact Us