PD-L2 Antibodies

Target Information

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

B7 dendritic cell molecule; B7-DC; B7DC; B7dc; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; Cd273; F730015O22Rik; MGC124039; MGC124040; MGC142238; MGC142240; OTTMUSP00000015822; PD-; PD-1 ligand 2; PD-1-ligand 2; PD-L2; PD1L2; PDCD1 ligand 2; PDCD1L2; PDCD1LG2; Pdcd1lg2; PDL2; Pdl2; Programmed cell death 1 ligand 2; Programmed death ligand 2